115 年 國立臺灣大學職能治療學系研究所《英文文獻閱讀測驗》

第 一、 題

請閱讀以下摘要,並回答下列的問題。

  1. 請使用中文說明此研究之目的?(5%)
  2. 請使用中文說明此研究是如何進行?(5%)
  3. 請使用中文說明研究結果(請使用數字佐證)如何回應初始的研究目的?(10%)

Abstract
Purpose: Cerebral/cortical visual impairment (CVI) is a leading cause of pediatric visual impairment and is frequently associated with abnormal ocular motility. Eye tracking has previously been used to characterize oculomotor function in CVI. The purpose of this study was to evaluate the utility of eye tracking in diagnosis, categorization, and prognostication of CVI.
Design: Prospective longitudinal study.
Participants: Thirty-nine children with CVI and 41 age-matched controls.
Methods: Children with CVI underwent 4 eye tracking sessions over 1 year, and age-matched controls completed 1 eye tracking session. Fixations and saccades were labeled by the eye tracking software and used to compute 9 oculomotor features. In children with CVI, unsupervised data-driven clustering analysis using these 9 features was performed to identify 3 CVI eye tracking oculomotor groups. Clinical and demographic characteristics of eye tracking oculomotor groups were compared.
Main Outcome Measures: (1) Area under the curve (AUC) for eye tracking oculomotor features in classifying patients with CVI and controls; (2) differences between 3 CVI eye tracking oculomotor groups on clinical and demographic characteristics; and (3) change in visual acuity (VA) over 1 year in 3 CVI eye tracking oculomotor groups.
Results: Six oculomotor features (fixation and saccade latency, frequency, and off-screen proportion) had an AUC ≥ 0.90 in classifying children with CVI and controls (P<0.0001). Cerebral/cortical visual impairment eye tracking oculomotor groups had significantly different VA (P<0.0001) and change in VA over 1 year (P¼ 0.049). Patients in group B, who had the greatest improvement in VA, were younger and had higher rates of term hypoxic ischemic encephalopathy.
Conclusions: Eye tracking measures of oculomotor function accurately distinguish between children with CVI and age-matched controls. Clustering analysis revealed 3 CVI eye tracking oculomotor groups with prognostic significance. Eye tracking shows promise as an objective, quantitative measure of oculomotor function in CVI that may in future be useful in both clinical practice (for longitudinal assessment, prognostication, and guiding individualized interventions) and research (as an outcome measure or method to stratify patients in clinical trials).

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這一題的完整詳解

這是一篇關於腦視皮質損傷 (Cerebral/cortical visual impairment, CVI) 的研究摘要。題目要求根據摘要,說明研究目的、進行方式,以及研究結果如何回應研究目的。

核心觀念:
理解研究摘要的結構,包含目的 (Purpose)、設計 (Design)、參與者 (Participants)、方法 (Methods)、主要測量指標 (Main Outcome Measures)、結果 (Results) 和結論 (Conclusions)。

解題步驟:

  1. 研究目的 (Purpose):

    • 摘要開頭的 Purpose 部分明確指出:「The purpose of this study was to evaluate the utility of eye tracking in diagnosis, categorization, and prognostication of CVI.」
    • 中文翻譯:本研究的目的是評估眼動追蹤在 CVI 的診斷、分類和預後評估上的應用性。

    【答案】本研究的目的在於評估眼動追蹤技術在腦視皮質損傷 (CVI) 的診斷、分類以及預後評估方面的應用性。

  2. 研究進行方式 (Design & Methods):

    • Design: 摘要中的 Design 部分說明是「Prospective longitudinal study」(前瞻性縱向研究)。
    • Participants: 參與者包含 39 名 CVI 兒童和 41 名年齡相符的對照組兒童。
    • Methods:
      • CVI 兒童進行了為期 1 年的 4 次眼動追蹤測試。
      • 對照組兒童進行了 1 次眼動追蹤測試。
      • 眼動追蹤軟體用於標記注視點 (fixations) 和掃視 (saccades),並計算出 9 項眼動肌動功能特徵 (oculomotor features)。
      • 對 CVI 兒童進行無監督式資料驅動的聚類分析 (unsupervised data-driven clustering analysis),利用這 9 項特徵找出 3 個 CVI 眼動追蹤肌動功能群組。
      • 比較這 3 個 CVI 眼動追蹤肌動功能群組在臨床和人口統計學特徵上的差異。
      • 主要測量指標 (Main Outcome Measures) 包括:(1) 眼動追蹤肌動功能特徵用於區分 CVI 病患與對照組的曲線下面積 (AUC);(2) 3 個 CVI 眼動追蹤肌動功能群組在臨床和人口統計學特徵上的差異;(3) 3 個 CVI 眼動追蹤肌動功能群組在 1 年內的視力 (VA) 變化。

    【答案】此研究採用前瞻性縱向研究設計。研究對象包含 39 名 CVI 兒童與 41 名年齡相符的對照組兒童。CVI 兒童在一年內接受了四次眼動追蹤測試,對照組則接受一次。研究方法是利用眼動追蹤軟體標記參與者的注視點與掃視,計算出九項眼動肌動功能特徵。接著,對 CVI 兒童進行無監督式聚類分析,以這九項特徵將其分成三個眼動肌動功能群組,並比較這些群組在臨床與人口統計學特徵上的差異,同時也測量了其一年內的視力變化。主要測量指標包括眼動肌動功能特徵分類 CVI 病患與對照組的曲線下面積 (AUC),以及 CVI 群組間在臨床特徵與視力變化上的差異。

  3. 研究結果如何回應研究目的 (Results & Purpose):

    • 研究目的在於評估眼動追蹤在 CVI 的「診斷」、「分類」和「預後評估」上的應用性。
    • 診斷 (Diagnosis):
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第 三、 題

請閱讀以下某篇文獻的內文,並回答下列的問題。

  1. 請說明與此二段落相關的主要發現。(10%)
  2. 請說明研究結果能否支持「自閉症類群障礙個案具有社會認知損傷」,並解釋原因。(10%)

Autism is conceptualised clinically, and in scientific research, by core deficits in social communication, inter-action and emotional reciprocity, deficits in non-verbal communicative behaviours used for social interaction and an absence of interest in peers (APA, 2013). In theory, this should translate into poor information transfer with others. These results, however, are the first empirical evidence that suggest the difficulties in autistic communication are apparent only when interacting with non-autistic people, and are alleviated when interacting with autistic people. This is evidenced by our finding that autistic and non-autistic people do not significantly differ in how accurately they recall information from peers of the same neurotype but that selective difficulties occur when autistic and non-autistic people are sharing information. This occurs along-side significantly lower rapport within mixed groups.

These results challenge traditional assumptions of autistic social impairment. The findings are inconsistent with the social-cognitive deficit narrative of autism. We found a selective breakdown of information transfer and rapport occurred in mixed autistic-non-autistic interactions, indicating that the diagnostic status of an interlocutor plays a critical role in both the quality and enjoyment of and interaction, for both autistic and non-autistic people. The quality of transfer of information within all autistic chains did not differ from information transfer in all non-autistic chains, indicating that autistic peoples' abilities to share information and build rapport do not significantly differ from their non-autistic counterparts.

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這一題的完整詳解

這是一篇探討自閉症類群障礙 (Autism Spectrum Disorder, ASD) 患者在社交互動中的溝通特徵的研究。題目要求說明研究的主要發現,以及結果是否支持自閉症患者有社會認知損傷。

核心觀念:
理解自閉症的傳統觀點(核心缺陷在於社會溝通、互動、情感互惠等),以及本研究提出的挑戰性發現,即溝通困難的表現取決於互動對象的神經類型 (neurotype)。

解題步驟:

  1. 主要發現 (Main Findings):

    • 文章開頭定義了自閉症的傳統觀點,即核心缺陷在於社會溝通、互動、情感互惠、非語言溝通行為以及對同儕的興趣缺乏。
    • 然而,本研究的發現與此傳統觀點不同。
    • 主要發現 1: 溝通困難僅在與「非自閉症人士」互動時顯現,而在與「自閉症人士」互動時則會減輕。
    • 主要發現 2: 自閉症與非自閉症人士在回憶同類型神經類型同儕的資訊時,準確度無顯著差異。
    • 主要發現 3: 當自閉症與非自閉症人士在分享資訊時,會出現選擇性的困難。
    • 主要發現 4: 在混合的自閉症與非自閉症群體中,關係親密度 (rapport) 顯著較低。
    • 主要發現 5: 互動對象的神經類型在互動的品質和愉悅度上扮演關鍵角色。
    • 主要發現 6: 在所有自閉症者組成的溝通鏈中,資訊傳遞的品質與所有非自閉症者組成的溝通鏈無差異。
    • 主要發現 7: 自閉症者的資訊分享和建立關係親密度的能力,與非自閉症者無顯著差異。

    【答案】此二段落的主要發現是,自閉症患者的溝通困難並非普遍存在,而是僅在與非自閉症人士互動時顯現,且在與自閉症人士互動時會有所改善。研究發現,自閉症與非自閉症人士在回憶同類型神經類型的同儕資訊時準確度無顯著差異,但與不同類型神經類型者分享資訊時會出現選擇性的困難,同時在混合群體中關係親密度較低。

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第 四、 題

請閱讀以下摘要,並用中文回答下列問題:

  1. 根據摘要中的Evidence synthesis 結果,請說明目前AI 在復健領域的研究主要集中在哪些復健領域、醫療階段,以及主要技術整合工具?(10%)
  2. 摘要的Conclusions 指出,儘管 AI在復健領域的進展迅速,但要真正落實到臨床實務仍面臨許多關鍵問題。請說明目前AI 復健研究在方法上有哪些主要缺點?(10%)

Abstract
Introduction: Artificial intelligence (AI) is revolutionizing many fields of science, including medicine, by enhancing diagnostic, therapeutic, and decision-making processes. However, understanding how AI can be truly useful in everyday clinical practice remains challenging. This living review systematically investigates current clinical applications of AI in the rehabilitation field, clarifies key concepts, and identifies knowledge gaps.
Evidence acquisition: PubMed, Scopus, WOS/Embase, and PEDro were systematically searched from December 1, 2014, to December 1, 2024. Retrieved articles were independently screened by two reviewers, with a third reviewer resolving any disagreements. Extracted data (including bibliometric, clinical, and AI-related variables) were synthesized into a synoptic table using a semi-automated Python pipeline. Reporting adhered to PRISMA guidelines, and the review protocol was registered in the PROSPERO database (CRD420250622434).
Evidence synthesis: Of 4193 records identified, 240 studies applying AI for rehabilitative purposes met the inclusion criteria. Most studies focused on neurological (57.9%) and orthopedic (22.7%) rehabilitation, particularly involving stroke, Parkinson's disease, and amputation, with research activity mainly concentrated in China (24.6%) and the USA (16.7%). AI has been tested across all stages of the medical process, with a slight predominance in intervention (23.8%), followed by prognosis (17.5%), assessment (16.7%), diagnosis (12.9%), and monitoring (12.5%). It was frequently integrated with wearable sensors, robotic systems, and digital technologies, especially inertial measurement units, surface EMG, mobile apps and EEG. Most AI studies in rehabilitation used raw (37.9%) or tabular data (27.5%), with multimodal inputs in only 11.3%. Over half lacked a comparator (50.8%). Supervised learning (70.8%) and classical machine learning (43.8%) predominated, while external validation (5.8%) and explainability (10.2%) were rarely applied.
Conclusions: Al applications in rehabilitation are rapidly expanding, particularly in neurological and orthopedic fields where data-driven and technology-assisted approaches prevail. While this progress is promising, current evidence remains largely based on supervised learning with small, single-type datasets, limited external validation, and scarce explainability, critical issues that must be addressed to enable reliable translation into clinical practice.

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這一題的完整詳解

這是一篇關於人工智慧 (AI) 在復健領域應用的系統性回顧。題目要求根據摘要中的「Evidence synthesis」部分,說明 AI 在復健領域研究的集中方向,以及「Conclusions」部分指出的研究方法上的主要缺點。

核心觀念:
理解系統性回顧摘要的結構,特別是「Evidence synthesis」(證據綜合)和「Conclusions」(結論)兩部分,並能从中提取關鍵資訊。

解題步驟:

  1. AI 在復健領域研究的集中方向 (Evidence synthesis):

    • 復健領域 (Rehabilitation fields):
      • 摘要指出:「Most studies focused on neurological (57.9%) and orthopedic (22.7%) rehabilitation, particularly involving stroke, Parkinson's disease, and amputation...」
      • 中文翻譯:大多數研究集中在神經復健 (57.9%) 和骨科復健 (22.7%),特別是涉及中風、帕金森氏症和截肢的案例。
    • 醫療階段 (Medical process stages):
      • 摘要指出:「AI has been tested across all stages of the medical process, with a slight predominance in intervention (23.8%), followed by prognosis (17.5%), assessment (16.7%), diagnosis (12.9%), and monitoring (12.5%).」
      • 中文翻譯:AI 被測試用於醫療過程的所有階段,其中介入 (intervention, 23.8%) 佔輕微優勢,其次是預後 (prognosis, 17.5%)、評估 (assessment, 16.7%)、診斷 (diagnosis, 12.9%) 和監測 (monitoring, 12.5%)。
    • 主要技術整合工具 (Integrated technologies):
      • 摘要指出:「It was frequently integrated with wearable sensors, robotic systems, and digital technologies, especially inertial measurement units, surface EMG, mobile apps and EEG.」
      • 中文翻譯:AI 經常與穿戴式感測器、機器人系統和數位技術整合,特別是慣性感測器單元 (inertial measurement units, IMUs)、表面肌電圖 (surface EMG)、行動應用程式 (mobile apps) 和腦電圖 (EEG)。

    【答案】根據摘要中的 Evidence synthesis 結果,目前 AI 在復健領域的研究主要集中在:

    • 復健領域: 神經復健 (佔 57.9%) 和骨科復健 (佔 22.7%),尤其關注中風、帕金森氏症和截肢等病症。
    • 醫療階段: AI 被應用於醫療過程的各個階段,其中以介入 (intervention, 23.8%) 最為普遍,其次為預後 (17.5%)、評估 (16.7%)、診斷 (12.9%) 和監測 (12.5%)。
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第 五、 題

請依據以下論文摘要,用中文回答問題。

  1. 翻譯此題目。(5%)
  2. 此系統回顧納入論文的篩選條件為何?(5%)
  3. 納入分析的論文,主要包含哪些介入內容?(5%)
  4. 文中指出具有較佳成效的介入特性為何?(5%)

Abstract
Importance: As populations age, promoting health span has become a public health priority. Occupational therapy is well positioned to contribute through health promotion and primary prevention, yet its effectiveness remains underexplored.
Objective: To examine the effectiveness of occupational therapy interventions in health promotion and primary prevention for adults, as measured by health-related outcomes such as occupational performance, quality of life (QoL), well-being, and participation.
Data Sources: The PubMed, CINAHL, Cochrane Library, ProQuest, and Wiley Online Library databases were searched in February 2025.
Study Selection and Data Collection: Following Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020 guidelines, eligible studies were randomized controlled trials (RCTs) of interventions led by or aligned with occupational therapy in adult health promotion or primary prevention. Risk of bias was assessed using the Joanna Briggs Institute (2024) checklist. Data were narratively synthesized because of heterogeneity.
Findings: Twelve RCTs (2020-2024) were included, covering diverse populations and settings. Interventions included workplace health promotion, home modifications, telerehabilitation, exergaming, and environmental or behavioral strategies. Positive effects were noted in fall reduction, coping, physical performance, and health-related QoL. Interventions rooted in occupational frameworks and delivered by trained occupational therapy practitioners showed greater effectiveness. Variability in intensity and delivery limited comparability.
Conclusions and Relevance: Occupational therapy interventions can support adult health promotion and disease prevention when contextual, person-centered, and occupation-based. Further research should address younger adults, leisure occupations, and intervention intensity. These findings support integrating occupational therapy into public health strategies to enhance health span and reduce reliance on reactive care.

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這一題的完整詳解

這是一篇關於職能治療介入在成人健康促進和初級預防中有效性的系統性回顧摘要。題目要求翻譯題目、說明篩選條件、納入論文的介入內容,以及具有較佳成效的介入特性。

核心觀念:
理解系統性回顧摘要的結構,特別是「Objective」(目標)、「Data Sources」(資料來源)、「Study Selection and Data Collection」(研究篩選與資料收集)和「Findings」(發現)等部分,並能从中提取關鍵資訊。

解題步驟:

  1. 翻譯此題目 (Translate the title):

    • 題目為:「Effectiveness of Occupational Therapy Interventions in Health Promotion and Primary Prevention for Adults: A Systematic Review」
    • 中文翻譯:成人健康促進與初級預防中職能治療介入的有效性:一項系統性回顧。

    【答案】成人健康促進與初級預防中職能治療介入的有效性:一項系統性回顧。

  2. 此系統回顧納入論文的篩選條件為何 (Study Selection and Data Collection):

    • 摘要指出:「Following Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020 guidelines, eligible studies were randomized controlled trials (RCTs) of interventions led by or aligned with occupational therapy in adult health promotion or primary prevention.」
    • 中文翻譯:遵循系統性回顧與統合分析報告項目 (PRISMA) 2020 指南,符合條件的研究必須是成人健康促進或初級預防領域,由職能治療主導或與職能治療相關的隨機對照試驗 (RCTs)。

    【答案】此系統回顧納入的論文篩選條件為:

    • 遵循 PRISMA 2020 指南。
    • 研究對象為成人。
    • 研究內容為健康促進 (health promotion) 或初級預防 (primary prevention)。
    • 研究設計為隨機對照試驗 (Randomized Controlled Trials, RCTs)。
    • 介入措施由職能治療主導 (led by occupational therapy) 或與職能治療相關 (aligned with occupational therapy)。
  3. 納入分析的論文,主要包含哪些介入內容 (Findings):

    • 摘要指出:「Interventions included workplace health promotion, home
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